Oracle has released version 5.0 of its type-2 virtualization platform VM VirtualBox. Starting with a public beta in April this year and some more test builds and a release candidate later the product is now released. Oracle also already released an update (version 5.0.2.) containing some fixes for version 5.0 already.
There are known problems with VirtualBox 5.0.2 on Windows 10 hosts and with Windows 10 guests. Some of the problems are fixed in the most recent test build which can be found here.