Quoting from the Symantec official announcement:

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NetBackup 6.5 introduces a host of new features and enhancements including native disk-based backup, data deduplication, deep integration with intelligent backup appliances and VTLs, heterogeneous snapshot management, granular recovery for critical applications and virtual machines, and innovative new licensing and pricing programs.

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NetBackup leverages VMware Consolidated Backup, a capability provided by VMware, to guarantee consistency and remove the backup burden from the primary VMware server host. NetBackup 6.5 also goes a step further, by introducing a breakthrough capability to enable a single image-level backup to deliver both full-image or granular file-level recovery. Finally, VMware backups can be performed to tape or disk, and can apply the new PureDisk Deduplication Option for deduplication and replication of VMware backups…